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Broncho-obstructive syndrome in pediatrician’s practice (clinical cases)

https://doi.org/10.15690/rpj.v4i4.2718

Abstract

Background. With the development of broncho-obstructive syndrome (BOS), spasm, edema, hypercrinia and bronchial dyscrinia occur. Increasing airflow resistance can complicate the course of diseases of the respiratory system. Broncho-obstructive syndrome coexists many pathologies, including cardiovascular diseases, gastrointestinal diseases and other abnormal developments of internal organs. The causes of this syndrome are diverse, including bronchial asthma, abnormal developments of the bronchopulmonary system, gastroesophageal reflux, cystic fibrosis and congenital heart diseases. The purpose of this study was to analyze and describe clinical cases of pediatric patients with BOS.

Clinical cases description. The article presents clinical cases of patients who were treated at the State Budgetary Healthcare Institution of Republic of Crimea “Republic Children’s Clinical Hospital” at different times, who developed BOS against the background of Nijmegen Breakage Syndrome and aspiration of a foreign body (feather from a pillow) into the bronchi. Both clinical cases show the importance of comprehensive, and most importantly, timely diagnostic procedure. In clinical case No. 1, the medical history of patient N. with Nijmegen Breakage Syndrome is described. The pathology was revealed owing to a comprehensive diagnostic procedure. Representatives of patient N. appealed to the State Budgetary Healthcare Institution of Republic of Crimea “Republic Children’s Clinical Hospital” in connection with the development of symptoms of bronchial obstruction. Clinical case No. 2 describes the untimely diagnosis of a radiolucent bronchial foreign body. In this situation, the ambiguity of the clinical picture and, as a result, the search for other pathologies cost the child his life.

Conclusion. Broncho-obstructive syndrome is associated with a variety of pathologies that are not limited to problems with the respiratory system. It is important to be able to identify symptoms in patients that will indicate the cause of the developed BOS.

About the Authors

Natalia V. Lagunova
V.I. Vernadsky Crimean Federal University; Republic Children’s Clinical Hospital
Russian Federation

MD, PhD, Professor.

Simferopol



Tamara V. Semenchuk
V.I. Vernadsky Crimean Federal University
Russian Federation

MD, PhD.

5/7 Lenin Boulevard, Simferopol, 295051; +7 (978) 598-16-70



Elena I. Kuntsevich
V.I. Vernadsky Crimean Federal University
Russian Federation

MD, PhD.

Simferopol



Natalia O. Miagkaia
V.I. Vernadsky Crimean Federal University
Russian Federation

Student.

Simferopol



Julia S. Saenko
V.I. Vernadsky Crimean Federal University
Russian Federation

Student.

Simferopol



References

1. Bolezni organov dykhaniya u detei: Practical guide. Tatochenko VK, ed. Moscow: Borges; 2019. (In Russ).

2. Natsional’naya programma “Bronkhial’naya astma u detei. Strategiya lecheniya i profilaktika”. Russian respiratory society; Pediatric Respiratory Society; Federation of pediatricians of the CIS countries. Geppe NA, sci. ed. Moscow; 2019. (In Russ).

3. Kuzmenko NB, Shcherbina AYu. Classification of primary immunodeficiencies as a reflection of modern ideas about their pathogenesis and therapeutic approaches. Russian Journal of Pediatric Hematology and Oncology. 2017;4(3):51–57. (In Russ). https://doi.org/10.17650/2311-1267-2017-4-3-51-57

4. Illi S, Von Mutius E, Lau S, et al. Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort study. Lancet. 2006;368(9537):763–770. https://doi.org/10.1016/S0140-6736(06)69286-6

5. Zaitseva OV. Bronchial obstruction in children. Pediatrics. Journal n.a. G.N. Speransky. 2005;84(4):94–104. (In Russ).

6. Antonov OV. Nauchnye, metodicheskie i organizatsionnye podkhody k profilaktike vrozhdennykh porokov razvitiya u detei. [dissertation]. Omsk; 2007. (In Russ).

7. Rozinova NN. Sindrom Vil’yamsa-Kempbella i lobarnaya emfizema — redkie poroki razvitiya legkikh s edinoi patogeneticheskoi osnovoi. Trudnyi patsient. 2009;7(8-9):32–34. (In Russ).

8. Shankar G, Kothari P, Sarda D, et al. Pneumonectomy in a child with congenital bronchiectasis: A case report and review of literature. Ann Thorac Med. 2006;1(2):81–83. https://doi.org/10.4103/1817-1737.27107

9. Rustamova MT, Liverko IV, Khayrullaeva SS, Sahova B. Frequency, nature and risk factors of lesions of the esophagogastroduodenal zone in patients with bronchial asthma. Experimental and Clinical Gastroenterology Journal. 2020;176(4):54– 58. (In Russ). https://doi.org/10.31146/1682-8658ecg-176-4-54-58

10. Zhang M, Pandolfino JE, Zhou X, et al. Assessing different diagnostic tests for gastroesophageal reflux disease: a systematic review and network metaanalysis. Ther Adv Gastroenterol. 2019;21:12:1756284819890537. https://doi.org/10.1177/1756284819890537

11. Mukhamedjanova MKh, Jumayeva MF, Nurova NS. Clinical features of the comorbid state of arterial hypertension and bronchial asthma. Asian journal of pharmaceutical and biological research. 2021;10(3). (In Russ).

12. Abrosimov VN, Ponomareva IB, Nizov AA, Solodun MV. On respiratory manifestations of gastroesophageal reflux disease. Terapevticheskii arkhiv. 2018;(8):131–136. (In Russ). https://doi.org/10.26442/terarkh2018908131-136

13. Klyaritskaya IL, Krivoy VV, Rabotyagova YuS. Extra-esophageal manifestations of gastroesophageal reflux disease. Crimean Journal of Internal Diseases. 2019;(4):14–22. (In Russ).

14. Apenchenko YuS, Gnusaev SF, Rozov DN, et al. The course of bronchial asthma with gastroesophageal reflux disease in children. Journal of New Medical Technologies. 2018;25(3):7–14. (In Russ). https://doi.org/10.24411/1609-2163-2018-16057

15. Burkov SG, Alekseeva EP, Arutyunov AG, Shipova TM. Vliyanie antisekretornoi terapii omeprazolom na nochnye simptomy bronkhial'noi astmy pri ee sochetanii s GERB. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2008;(4):28–31. (In Russ).

16. 2023 GINA Report, Global Strategy for Asthma Management and Prevention. In: Global Initiative for Asthma: Official website. 2023. Available online: https://ginasthma.org/2023-gina-main-report. Accessed on December 21, 2023.

17. Fedorova SO, Kozlova NM. Gastroesophageal reflux disease associated with diseases of the respiratory tract. Acta biomedical scientifica. 2018;3(3):103–107. (In Russ). https://doi.org/10.29413/ABS.2018-3.3.16

18. Markovnin VR, Zavyalova AV, Votyakova OI. Combined course of bronchial asthma and gastroesophageal reflux disease in children. Bulletin of the Ivanovo Medical Academy. 2019;24(2):52–56. (In Russ).

19. Asadullaev SKh, Badalova SA, Shamsilidin I, et al. Risk factors and clinical manifestations of gastroesophageal reflux disease due to somatic diseases. Avicenna Bulletin. 2013;(1):74–78. (In Russ).

20. Borovik IO, Babinets LS, Shostak SYe, et al. Peculiarities of treating bronchial asthma associated with gastroesophageal reflux disease. Gastroenterologiya. 2014;(1):18-21.

21. Mukovistsidoz. Kapranov NI, Kashirskaya NYu, eds. Moscow: Medpraktika-M; 2014. (In Russ).

22. Registr bol’nykh mukovistsidozom v Rossiiskoi Federatsii. 2017 god. Voronkova AYu, Amelina EL, Kashirskaya NYu, et al. Moscow: Medpraktika-M; 2019. 68 p. (In Russ).

23. Kim J, Lyman B, Savant AP. Cystic fibrosis year in review 2022. Pediatr Pulmonol. 2023;58(11):3013–3022. https://doi.org/10.1002/ppul.26641

24. Amer HS, El-Anwar MW, Raafat A, et al. Laryngo-Tracheo-Bronchial Foreign Bodies in Children: Clinical Presentations and Complications. Iran J Otorhinolaryngol. 2017;29(92):155–159.

25. Bajaj D, Sachdeva A, Deepak D. Foreign body aspiration. J Thorac Dis. 2021;13(8):5159–5175. https://doi.org/10.21037/jtd.2020.03.94

26. Rance A, Mittaine M, Michelet M, et al. Delayed diagnosis of foreign body aspiration in children. Arch Pеdiatr. 2022;29(6):424– 428. https://doi.org/10.1016/j.arcped.2022.05.006

27. Shah R, McLear PW. Neck Abscess Caused by Feather Foreign Body. Otolaryngol Head Neck Surg. 2013;149(3):515–516. https://doi.org/10.1177/0194599813490897


Review

For citations:


Lagunova N.V., Semenchuk T.V., Kuntsevich E.I., Miagkaia N.O., Saenko J.S. Broncho-obstructive syndrome in pediatrician’s practice (clinical cases). Russian Pediatric Journal. 2023;4(4):129-136. (In Russ.) https://doi.org/10.15690/rpj.v4i4.2718

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